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KMID : 0816120010040020133
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Korean Journal of Pediatric Gastroenterolology and Nutrition
2001 Volume.4 No. 2 p.133 ~ p.141
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24 Hour Esophageal PH Monitoring in Preterm Infants
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Park Jeung-Hyun
Park Beom-Soo
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Abstract
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Purpose: Gastroesophageal reflux (GER) has been found to be the causative factors of apnea, stridor, feeding intolerance, poor weight gain, and sudden infants death syndrome (SIDS) in infants. GER is a well-described in infants and children, but only scant mention of the premature infants with GER can be found in the literature.
Methods: Esophageal pH was measured during 24 hour in 21 healthy preterm infants, using a silicone microelectrode with an external reference electrode connected to a portable recorder. The mean age of the patients was 29±8 days, mean gestational age was 30+5±2+0 weeks, mean birth weight was 1,468±329 g, mean postconceptional age was 34+6±1+4 weeks and mean weight was 1,750±329 g. We evaluated the following reflux parameters; number of acid reflux, number of long acid reflux, longest acid reflux minutes, and reflux index.
Results: Pathologic GER was detected in 12 (57%) subjects and most interesting parameters are reflux index and number of episodes with a pH<4 during 24 hour (high correlation with postprandial reflux index). Reflux was not correlated to gestational age, birth weight, age, postconceptional age, weight, sex and medication of the theophylline.
Conclusion: Gastroesophageal reflux is common in preterm infants, but it is usually not apparent, even with severe reflux.
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KEYWORD
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Gastroesophageal reflux, Preterm infants, 24 hour esophageal pH monitoring
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